Moreover, when we exposed TBL2‐deficient MDA‐MB‐231 cells to the AKT‐specific activator SC79, we observed that activated AKT was able to restore the proliferation capacity of these cells, providing further evidence that TBL2 impacts breast cancer cell proliferation via the AKT pathway (Figures S3E–G, Supporting Information). Here, TBL2 is linked to breast carcinoma.