Epithelial‐mesenchymal transition (EMT) has great significance in the CRC cell metastatic process.[18] We found that SLITRK4 significantly regulated the transcription factor Zeb‐mediated EMT process and mediated markers (E‐cadherin and Vimentin) (Figure S2d,e, Supporting Information). This evidence concerns the gene CDH1 and colorectal carcinoma.