PROS1 and soft tissue sarcoma: Similarly, two studies, which both focused on changes in gene expression as a means of predicting cancer prognosis [106, 107], found a clustering of mRNA expression changes of effector transcripts involved in m6A, m5C, m1A and m7G modification as well as proteins involved in other post-transcriptional processing, e.g. A to I editing RNA proteins, with different colorectal or soft-tissue sarcoma tumour types.