CTLA4 and colorectal carcinoma: Spatial transcriptomic analysis showed that the infiltration of CD68, CD4, and CTLA4 genes was higher in patient 21 (Fig. 4A) in which liver metastasis (CMS4) and primary CRC sites (CMS1) was observed compared to the infiltration of these genes in patient 17 (Fig. 4B) in liver metastasis (CMS3) of CRC (CMS2).