The set of novel isoform-switching genes included the proto-oncogene BRAF (BRAF-204, −0.88 log fold-change, adjusted P-value 1.183 × 10−5; BRAF-206, 1.13 log fold-change, adjusted P-value 1.085 × 10−2) for which cancer-causing mutations in lung adenocarcinoma have been previously identified (26). The gene discussed is BRAF; the disease is cancer.