CRP and osteoarthritis: In a separate study, elevated CRP levels were detected in association with inflammatory conditions, including autoimmune diseases (such as hypothyroidism, hyperthyroidism, rheumatoid arthritis, type-1 diabetes, and Crohn's disease) and non-autoimmune diseases (such as type-2 diabetes and osteoarthritis), suggesting that CRP is a marker of the risk of developing an inflammatory condition following radiation therapy (28).