However, some studies from the United States, Belgium, Northern Europe, and East Asia indicated that pathogenic variants in SLC26A4, MYO15A, OTOF, and CDH23 are probably the most common causes of autosomal recessive hearing loss, after the exclusion of variants in the DFNB1 locus (Hilgert et al., 2009; Duman and Tekin, 2012). The gene discussed is GJB2; the disease is autosomal dominant nonsyndromic hearing loss.