RUNX1 and acute lymphoblastic leukemia: Among them, B cells were divided into five clusters, and B cell cluster 1 was identified as B progenitor cell according to the specifically expressed gene, which was the highest proportion of all cellular cluster in ETV6-RUNX1 positive ALL patients, and was the only cell cluster with a significantly higher proportion in ETV6-RUNX1 positive ALL patients than in healthy pediatric samples.