In addition, MYDGF enhance s the numbers and proportions of M2φ in a dextran sodium sulfate (DSS)−induced colitis model (13), and it decreases M1φ polarization while increasing M2φ polarization in primary Kupffer cells and in nonalcoholic fatty liver disease mouse model (15). The gene discussed is MYDGF; the disease is metabolic dysfunction-associated steatotic liver disease.