CD4 and neoplasm: A large proportion of tumor-infiltrating immune cells were myeloid cells, mainly F4/80+ tumor associated macrophages (TAMs) and monocytic (Ly6Chigh), with smaller populations of CD4+ T cells, CD8+ T cells and granulocytic (Ly6G+) myeloid cells (Figure 1F, gating strategy shown in Supplementary Figure 3).