After multiple comparisons, we found that NSCLC patients with polysomy had a significantly higher incidence of EGFR L858R (p = 0.002), ARID1A (p = 0.025) and NRAS (p = 0.036) and significantly lower incidence of EGFR del19 (p = 0.041) mutation compared with those with MET negative. This evidence concerns the gene ARID1A and non-small cell lung carcinoma.