3’tRF-ThrCGT and CEA diagnostic efficiency was 0.827 (Figure 6A), 5 ‘tRF-GlyGCC and CA724 diagnostic efficiency was 0.848 (Figure 6B), 3’tRF-ThrCGT combined with the two tumor markers diagnostic rate was 0.911{95% CI 0.880–0.942} (Figure 6C). This evidence concerns the gene CEACAM5 and neoplasm.