In the analysis of any grade AEs, more cases of anorexia, alanine aminotransferase increase, neutropenia, alkaline phosphatase increase, nausea, fatigue, vomiting, blood creatinine increase, thrombocytopenia, and constipation were found in the ETC group (Table 4, Supplementary Figure S9). The gene discussed is GPT; the disease is Anorexia.