CDKN1B and neoplasm: Tumor expression of particular genes was found of prognostic/predictive value in acromegaly patients, These genes include basically CDH1 [37, 38] and SSTR2 [39, 40] but also CDKN1B [37] SNAI2 [41], FLNA [42], ARRB1 [43, 44], SNAI1 [45] RORC [45, 46] ESRP1 [38], and MKI67 [46].