MYC and leukemia: Similarly, IGF2BPs were reported to promote leukemia progression by maintaining the stability of m6A-labeled oncogenic mRNAs encoding self-renewal regulators HOXB4 and MYB, aldehyde dehydrogenase ALDH1A1 (Elcheva et al. 2020), the stem cell reprogramming factor LIN28B (which downregulates let-7 miRNA) (Zhou et al. 2017), and c-MYC (Zhu et al. 2021).