The Cytoscape analysis confirmed (with p < 0.01) the involvements of Wnt and Wnt-related signaling (Wnt signaling in cancer, Wnt target genes, Wnt5A-dependent internalization of FZD4, Wnt mediated activation of DVL, Hippo, Yap1, RUNX3 regules Wnt signaling, catenin Beta 1 (CTNNB1) and biding if TCF/LEF: CTNNB1 to target gene promoters). This evidence concerns the gene FZD4 and cancer.