GSTM1 and sensorineural hearing loss disorder: The results showed that SNHL is more common in SCA patients, especially those with Hb SS genotype, and they explained that this may be due to the impact of SCA on the labyrinthine microvasculature.[40] Another meta-analysis included 21 studies, and the results showed that the prevalence of SNHL in SCA was 20.5%, most likely due to the presence of circulatory disorders caused by the chronic inflammatory state of SCA.[41] In terms of treatment, early intervention is more important.