In addition, in older women with breast cancer, a high serum TSPO concentration has been shown to be significantly associated with the onset of postoperative delirium.[19] Contrary to previous studies, which showed that high TSPO concentrations are associated with worse clinical outcomes, in the present study we have shown that the plasma TSPO concentrations of patients with sepsis are low. The gene discussed is TSPO; the disease is breast carcinoma.