IL6 and Sepsis: The severity of sepsis is closely associated with IL-6, which not only plays a role in regulating inflammation, but also influences the release of other inflammatory mediators.[28,29] Our study results demonstrated that treatment with Sini Decoction acupoint application led to a more significant improvement in IL-6 levels compared to the control group, indicating its effective potential in ameliorating gastrointestinal dysfunction caused by sepsis-induced inflammation.