ROR1 and neoplasm: Despite the low protein levels of ROR1 detected in some normal human tissues [1, 2, 7], ROR1 has been profiled as a promising tumour target for the development of new therapeutic modalities due to its role enhancing tumour cell growth and survival, potentiating epithermal growth factor receptor signaling and promoting epithelial-mesenchymal transition and metastasis [1, 2, 9].