In addition, C-X-C motif chemokine (CXCL) 10, C-C motif chemokine (CCL) 11, IL-10, and IL-17A displayed significantly higher relative levels (FDR < 0.05, absolute FC > 1.2) in patients with colonic inflammation (UC, colonic CD, and ileocolonic CD) compared to HC (Figure 1, Supplementary Table 7). This evidence concerns the gene IL17A and Cowden disease.