As compared with the Foxr2 alone model, Foxr2 p53LOF tumors expressed higher levels of the oligodendroglial marker Olig2 and the neuronal progenitor marker DCX, and retained intermittent expression of the mature neuronal marker NeuN (Fig. 5F), recapitulating the mixed neuronal/oligodendroglial profile of human NB-FOXR2. Here, RBFOX3 is linked to neuroblastoma.