In ovarian cancer patients, subgroup A macrophages in ascites showed elevated levels of pro‐tumor markers (CD163, PCOLCE2, procollagen C‐endopeptidase enhancer 2, IL‐6), while subgroup B exhibited decreased levels of markers that promote tumor growth, expression of genes associated with interferon signaling and suppresses the immune function [180]. Here, PCOLCE2 is linked to ovarian cancer.