CALCOCO2 and myocardial infarction: have demonstrated that aloe emodin protects against myocardial infarction (MI) via inhibition of ROS production.[14] In the present study, we found that aloe emodin alleviated cardiac fibrosis through inhibition of NDP52‐induced mitophagy via repressing SH3 domain‐containing GRB2‐like protein B1 (SH3GLB1)‐mediated accumulation of mitoROS.