Mechanistically, lactate induced interaction of CBP/p300 and Snail1, leading to lactylation of Snail1, and further upregulated cardiac fibrosis after MI.[17] Emerging evidence has elucidated the potential relationship between lactylation and radiation‐induced cardiac fibrosis, which is facilitated through the accumulation of mitoROS to induce mitophagy activation. Here, SNAI1 is linked to myocardial infarction.