TNF and cancer: Neutrophils_S100A12 cells after IORT+Surgery exhibited specific enrichment in genes associated with the IL‐17 signaling pathway, Neutrophil extracellular trap formation, NOD‐like receptor signaling pathway, Platelet activation, PD‐L1 expression and PD‐1 checkpoint pathway in cancer, Apoptosis, Chemokine signaling pathway, Th17 cell differentiation, HIF‐1 signaling pathway, and TNF signaling pathway (Figure 6J).