Reducing CAV1 on BC cell-derived sEVs and decreasing CAV1 in lung epithelial cells resulted in fewer sEVs uptake by lung epithelial cells, suggesting that altering CAV1 on BC cell-derived sEVs and CAV1 expression in lung epithelial cells affects sEVs uptake by BEAS-2B cells (Fig. 2a-b). The gene discussed is CAV1; the disease is breast cancer.