Fs.Cr was found to regulate several additional key molecules involved in IBD, reducing the levels of TNF-α, IFN-γ, MDA and MPO, and increasing IL-17 SOD, GPX, CAT, and total GSH, thus demonstrating their role in decreasing UC severity by reducing oxidative damage, inflammation, and promoting mucosal repair 451. This evidence concerns the gene IL17A and inflammatory bowel disease.