Moreover, a diet supplemented with EA mitigates oxidative stress during colitis by bolstering Nrf2 signaling pathways in piglets treated with paraquat, protecting against intestinal injury by facilitating the maintenance of tight junction structure and intestinal barrier integrity, while also preserving jejunal and ileal morphology, including villus height, goblet cell number, and the ratio of villus height to crypt depth 349. Here, NFE2L2 is linked to colitis.