The overexpression of DDX5 in MCF-7 cells resulted in a significant increase in cell viability and a decrease in c-CASP3 levels, indicating that the overexpression of DDX5 reversed the antitumor effects of DOX and MA on tumor cells and led to a significant decrease in the anticancer effect (Fig. 9P-S). The gene discussed is DDX5; the disease is neoplasm.