IF staining also demonstrated that the expression levels of Caspase-1 and GSDMD-N in neurons were significantly lower in the SCI + HB group than in the SCI group, with a concurrent reduction in the numbers of caspase-1- and GSDMD-N-positive microglial cells, as illustrated in Figures S3A-H. This evidence concerns the gene CASP1 and hemoglobin measurement.