EGFR and colorectal carcinoma: MicroRNAs (miRNAs) play an important role in the development, progression, and metastatic potential of CRC, and act as biomarkers for the prediction of response to anti-vascular endothelial growth factors, anti-epidermal growth factor receptor (EGFR), and FOLFOX in metastatic CRC (Boussios et al., 2019).