This enzyme has been recognized as a key therapeutic agent for the treatment of acute lymphoblastic leukemia (ALL) and Hodgkin’s lymphoma over the past few decades.1,2 L-asparaginase also exhibits therapeutic potential in treating other blood and non-blood diseases, including pancreatic cancer, acute myeloid leukemia, and lymphosarcoma.3 The food industry also employs L-asparaginase to prevent the formation of acrylamide during high-temperature food processing. Here, ASPG is linked to blood disease.