This compound also gives a similar cytotoxic effect on several types of cancer cells, such as TNBC and non-TNBC,7,9,10 and in regular p53 and p53 mutant cancer cells.11 These broad-spectrum activities of PGV-1 on cancer types but on normal cells indicate that this compound has a unique mode of action on cancer cells that is interesting to further explore on some other specific types of cancer in HCC. This evidence concerns the gene TP53 and hepatocellular carcinoma.