This compound also gives a similar cytotoxic effect on several types of cancer cells, such as TNBC and non-TNBC,7,9,10 and in regular p53 and p53 mutant cancer cells.11 These broad-spectrum activities of PGV-1 on cancer types but on normal cells indicate that this compound has a unique mode of action on cancer cells that is interesting to further explore on some other specific types of cancer in HCC. This evidence concerns the gene TP53 and cancer.