Thirdly, we have demonstrated that [68Ga]Ga-HN11-1 effectively accumulates in tumor tissues in vivo and in vitro studies, particularly in A549-PD-L2 xenograft tumors, the T/M ratio of [68Ga]Ga-HN11-1 in A549-PD-L2 tumor xenograft model at 60 min after injection is reported as 27.92 ± 1.76. Here, PDCD1LG2 is linked to neoplasm.