MUC16 and hypertensive disorder: Given the significance of pre-eclampsia and its associated risks for both maternal and fetal health, coupled with the limited clinical research on the correlation between CA-125 serum levels and hypertensive disorders in pregnancy, along with the inconsistent findings reported in existing studies, and the importance of this issue led us to investigate the association between CA-125 and pre-eclampsia and estimated fetal weight (EFW).