Our findings indicate that HBO exposure significantly increases the expression levels of inflammatory and chemotactic cytokines, including Il6, Ccl2, Ccl3, and Cxcl10, consistent with previous research on normobaric hyperoxia-induced ALI (Li et al., 2011; Entezari et al., 2014; Dias-Freitas et al., 2016; Ning et al., 2020). Here, CCL2 is linked to acute respiratory distress syndrome.