In the promotion of tumor, NF-κB is an essential switch of anti-apoptosis genes, which include cellular inhibitors of apoptosis (c-IAPs), caspase-8–c-FLIP (FLICE inhibitory protein), A1 (also known as Bfl1), TNFR-associated factor 1 (TRAF1) and TRAF2 (97). The gene discussed is NFKB1; the disease is neoplasm.