For example, the research team led by P. Chen discovered that the lactate dehydrogenase A (LDHA)-mediated extracellular signal-regulated kinase (ERK) pathway can activate the transcriptional coactivators YAP1 and STAT3 in GBM cells, thereby upregulating the expression of CCL2 and CCL7. The gene discussed is CCL7; the disease is glioblastoma.