CD40LG and Lyme disease: Borrelia serology by ELISA (Sonicate IgG und IgM Elisa; Virotech, Germany) showed high concentrations of anti-borrelial IgG antibodies and in immunoblot (Borrelia ViraStripe® IgG and Borrelia ViraStripe® IgM, Viramed, Germany) a broad spectrum of B. burgdorferi specific bands were visible (Table 1), which is consistent with late Lyme borreliosis.