Furthermore, its physicochemical properties, pharmacokinetics, and biological activities support the efficacious effects of sulforaphane on AD, including druglikeness, BBB permeability, high intestinal absorption, glutathione S-transferase substrate (93.6%), immunostimulant (40.5%), neurotransmitter antagonist, and chemopreventive effects. Here, HPGDS is linked to Alzheimer disease.