Oral sulforaphane (5 to 15 mg/kg) treatment in ApoE-deficient (ApoE − / −) mice that were fed a high-fat diet resulted in the amelioration of dyslipidemia, the formation of atherosclerotic plaques, and the unstable phenotype, which is known to be a risk factor for AD (Liu et al. 2023). The gene discussed is APOE; the disease is metabolic syndrome.