ACHE and Alzheimer disease: Consequently, even though treatments for AD exist, such as acetylcholinesterase inhibitors, N-methyl-D-aspartate (NMDA) receptor antagonists, and monoclonal antibodies like aducanumab and leqembi, these drugs cannot cure AD and cause side effects (e.g., brain swelling, microbleeds, fatigue, nausea, etc.), and a significant proportion of individuals in developing nations lack access to these interventions (Mintun et al. 2021; Salloway et al. 2022).