These targets were found to be related to metabolite interconversion enzymes, modified residues, regulation of apoptotic signaling pathway, “Alzheimer’s Disease, Focal Onset”, NFKB1, SP1, and RELA, hsa-miR-17-5p, hsa-miR-16-5p, and hsa-miR-26b-5p. Here, SP1 is linked to early-onset autosomal dominant Alzheimer disease.