“Photodynamic therapy-induced NF-KB survival signaling”, “TNF related weak inducer of apoptosis signaling pathway”, “Alzheimer’s disease”, and “tauopathy” were annotated as important signaling pathways and diseases on how sulforaphane can protect against AD (Fig. 6A–C). Here, NFKB1 is linked to early-onset autosomal dominant Alzheimer disease.