DASH: Dietary Approaches to Stop Hypertension; ACE: angiotensin-converting enzyme; ARBs: angiotensin receptor blockers; CCBs: calcium channel blockers; BP: blood pressure; ALLHAT: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial; ISHIB: International Society of Hypertension in Blacks; AASK: African American Study of Kidney Disease and Hypertension; JSH: Japanese Society of Hypertension. The gene discussed is ACE; the disease is Hypertension.