WBC: white blood cell count; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; AST: aspartate aminotransferase; ALT: alanine aminotransferase; TSH: thyroid stimulating hormone; TB: tuberculosis; HIV: human immunodeficiency virus; IgM: immunoglobulin M; IgG: immunoglobulin G; NS1: nonstructural protein 1; CMV: cytomegalovirus; VCA: anti-viral capsid antigen; EBNA: Epstein-Barr nuclear antigen. The gene discussed is CD40LG; the disease is tuberculosis.