The significant reduction of haematological parameters (RBCs, WBCs, CD4, CD8, granulocytes, monocytes and platelets) in coinfected patients compared to monoinfected participants could be an indication that malaria-induced haemolysis, bone marrow dyserythropoiesis in particular and generalized haematopoietic system disorders have occurred [4, 35]. Here, CD4 is linked to malaria.