Compared with HCs, levels of IFN‐α2 (P = 0.0009), IFN‐γ (P = 0.0002), IL‐6 (P < 0.0001), IL‐10 (P < 0.0075), IL‐12p70 (P = 0.0005), IL‐18 (P < 0.0001), and IL‐23 (P < 0.0001) were significantly elevated in the AOSD cohort (Figure 5). Here, IL18 is linked to adult-onset Still disease.