PAX6 and neoplasm: Tumors were allowed to grow to approximately 100-150mm3, and animals were then divided into four groups of treatment, containing mice with comparable tumor volumes: IgG control (10 mg/Kg); anti-N1 (10 mg/Kg); anti-PD-1 (100 μg/mouse [27]); combo (aN1 + a-PD-1), delivered I.P. every other day.