Currently, MPCCs generated from PHHs and mouse fibroblasts have been utilized to further investigate the relationship between the inhibitory potential of the bile salt export pump (BSEP) and the risk of DILI [84], as well as to simulate the environment of non-alcoholic fatty liver disease (NAFLD) and evaluate valproic acid (VPA)-induced hepatic steatosis [85]. The gene discussed is ABCB11; the disease is metabolic dysfunction-associated steatotic liver disease.