The remaining annotations covered polymorphic pseudogenes either linked to a provisional phenotype (e.g. GUF1), or multifactorial diseases (e.g. CYP3A5), or with late onset diseases such as macular degeneration (e.g. ARMS2) (Fritsche et al. 2008), retinitis pigmentosa and azoospermia or oligospermia, OR2W3 (Ma et al. 2015; Aston et al. 2010). The gene discussed is CYP3A5; the disease is retinitis pigmentosa.