The remaining annotations covered polymorphic pseudogenes either linked to a provisional phenotype (e.g. GUF1), or multifactorial diseases (e.g. CYP3A5), or with late onset diseases such as macular degeneration (e.g. ARMS2) (Fritsche et al. 2008), retinitis pigmentosa and azoospermia or oligospermia, OR2W3 (Ma et al. 2015; Aston et al. 2010). Here, GUF1 is linked to macular degeneration.