The hemorrhage rates did not differ between groups (all ICH: HEP + TF, 23.3% vs. HEP, 32.1%, p = 0.35; symptomatic ICH: HEP + TF, 4.7% vs. HEP, 7.1%, p = 0.74). The gene discussed is TF; the disease is hepatoerythropoietic porphyria.