Additionally, immunofluorescent staining with the protein gene product 9.5 (PGP9.5), a pan-neuronal marker widely used to assess peripheral neuropathy,45 in the paw glabrous skin revealed a significant decrease in IENF in both male and female Dj-1−/− mice compared with wild-type mice (Fig. 2D). The gene discussed is UCHL1; the disease is peripheral neuropathy.