PIK3CA and neoplasm: As a tumor suppressor in PCa, switch defective (SWI)/sucrose non‐fermentable (SNF)‐ related, matrix‐associated, actin‐dependent regulator of chromatin subfamily c member 1 (SMARCC1) exhibits low expression levels, which can lead to the activation of the PI3K/AKT pathway, upregulation of cyclin D1/E1, and downregulation of cyclin‐dependent kinase inhibitor (CKI), thereby promoting PCa proliferation and facilitating EMT [68].