KRAS and cancer: Analysis of the Hallmark pathways revealed that multiple cancer-related pathways were activated in DCP1a-knockout and/or DCP1b-knockout cells, such as apoptosis, E2F targets, MYC targets, the mTOR signaling pathway, the G2/M checkpoint pathway, the KRAS signaling pathway, and the epithelial–mesenchymal transition pathway (Figure 4C).